"Good on them , it all helps "
Exactly how does the PCR test help?
The PCR test cannot distinguish the infectious live virus from residual dead virus or viral fragments from previous infection. Therefore, many, if not most, “cases” have no real meaning in terms of medical status or transmission potential – further misleading clinicians and policymakers alike.
Problems and inconsistencies with PCR testing have been documented extensively non standardised specimen collection techniques; no gold standard test yet identified; different tests used in different labs; no standardised acceptable Ct values; inconsistent quality assurance
programs; false positives; identification of irrelevant dead viral genetic material which can persist for months after infection; potential contamination of specimens, to name a few.
We have an epidemic of false test results not an epidemic of disease.
People need to realise that the test regime is scientifically nonsensical. |
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"Good on them , it all helps
Exactly how does the PCR test help?
The PCR test cannot distinguish the infectious live virus from residual dead virus or viral fragments from previous infection. Therefore, many, if not most, “cases” have no real meaning in terms of medical status or transmission potential – further misleading clinicians and policymakers alike.
Problems and inconsistencies with PCR testing have been documented extensively non standardised specimen collection techniques; no gold standard test yet identified; different tests used in different labs; no standardised acceptable Ct values; inconsistent quality assurance
programs; false positives; identification of irrelevant dead viral genetic material which can persist for months after infection; potential contamination of specimens, to name a few.
We have an epidemic of false test results not an epidemic of disease.
People need to realise that the test regime is scientifically nonsensical."
You'd not test instead? |
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By (user no longer on site)
over a year ago
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"Good on them , it all helps
Exactly how does the PCR test help?
The PCR test cannot distinguish the infectious live virus from residual dead virus or viral fragments from previous infection. Therefore, many, if not most, “cases” have no real meaning in terms of medical status or transmission potential – further misleading clinicians and policymakers alike.
Problems and inconsistencies with PCR testing have been documented extensively non standardised specimen collection techniques; no gold standard test yet identified; different tests used in different labs; no standardised acceptable Ct values; inconsistent quality assurance
programs; false positives; identification of irrelevant dead viral genetic material which can persist for months after infection; potential contamination of specimens, to name a few.
We have an epidemic of false test results not an epidemic of disease.
People need to realise that the test regime is scientifically nonsensical."
Best you use your obviously incredible knowledge and come up with a better solution then. I'm sure the government will be falling over themselves to hear it. |
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By (user no longer on site)
over a year ago
|
"Good on them , it all helps
Exactly how does the PCR test help?
The PCR test cannot distinguish the infectious live virus from residual dead virus or viral fragments from previous infection. Therefore, many, if not most, “cases” have no real meaning in terms of medical status or transmission potential – further misleading clinicians and policymakers alike.
Problems and inconsistencies with PCR testing have been documented extensively non standardised specimen collection techniques; no gold standard test yet identified; different tests used in different labs; no standardised acceptable Ct values; inconsistent quality assurance
programs; false positives; identification of irrelevant dead viral genetic material which can persist for months after infection; potential contamination of specimens, to name a few.
We have an epidemic of false test results not an epidemic of disease.
People need to realise that the test regime is scientifically nonsensical."
Says who?  |
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"Good on them , it all helps
Exactly how does the PCR test help?
The PCR test cannot distinguish the infectious live virus from residual dead virus or viral fragments from previous infection. Therefore, many, if not most, “cases” have no real meaning in terms of medical status or transmission potential – further misleading clinicians and policymakers alike.
Problems and inconsistencies with PCR testing have been documented extensively non standardised specimen collection techniques; no gold standard test yet identified; different tests used in different labs; no standardised acceptable Ct values; inconsistent quality assurance
programs; false positives; identification of irrelevant dead viral genetic material which can persist for months after infection; potential contamination of specimens, to name a few.
We have an epidemic of false test results not an epidemic of disease.
People need to realise that the test regime is scientifically nonsensical."
And perhaps you need to realise that it's the best thing we have at the moment and just letting the virus run roughshod throughout the country is a ridiculous alternative. |
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"Good on them , it all helps
Exactly how does the PCR test help?
The PCR test cannot distinguish the infectious live virus from residual dead virus or viral fragments from previous infection. Therefore, many, if not most, “cases” have no real meaning in terms of medical status or transmission potential – further misleading clinicians and policymakers alike.
Problems and inconsistencies with PCR testing have been documented extensively non standardised specimen collection techniques; no gold standard test yet identified; different tests used in different labs; no standardised acceptable Ct values; inconsistent quality assurance
programs; false positives; identification of irrelevant dead viral genetic material which can persist for months after infection; potential contamination of specimens, to name a few.
We have an epidemic of false test results not an epidemic of disease.
People need to realise that the test regime is scientifically nonsensical."
IN YOUR OPINION
As twitter would say
This fake news is contested by the truth ...... |
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By (user no longer on site)
over a year ago
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"Good on them , it all helps
Exactly how does the PCR test help?
The PCR test cannot distinguish the infectious live virus from residual dead virus or viral fragments from previous infection. Therefore, many, if not most, “cases” have no real meaning in terms of medical status or transmission potential – further misleading clinicians and policymakers alike.
Problems and inconsistencies with PCR testing have been documented extensively non standardised specimen collection techniques; no gold standard test yet identified; different tests used in different labs; no standardised acceptable Ct values; inconsistent quality assurance
programs; false positives; identification of irrelevant dead viral genetic material which can persist for months after infection; potential contamination of specimens, to name a few.
We have an epidemic of false test results not an epidemic of disease.
People need to realise that the test regime is scientifically nonsensical.
IN YOUR OPINION
As twitter would say
This fake news is contested by the truth ......"
For gods sake Oxfords Centre for evidence based medicine have been raising this for months.
The current number of cycles used in the tests is as stated above picking up people who could have had the disease weeks if not months ago. They are no longer infectious so are no longer a threat.
We are asking them and their contacts to isolate unnecessarily.
Reduce the number of cycles used in the labs so that you are targeting those that are a risk thus reduce the strain on test and trace and the number of people being asked to isolate. |
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"
For gods sake Oxfords Centre for evidence based medicine have been raising this for months.
The current number of cycles used in the tests is as stated above picking up people who could have had the disease weeks if not months ago. They are no longer infectious so are no longer a threat.
We are asking them and their contacts to isolate unnecessarily.
Reduce the number of cycles used in the labs so that you are targeting those that are a risk thus reduce the strain on test and trace and the number of people being asked to isolate."
...and in the process end up with an increase in false negatives.
Can't think why they haven't done this... |
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By (user no longer on site)
over a year ago
|
"
For gods sake Oxfords Centre for evidence based medicine have been raising this for months.
The current number of cycles used in the tests is as stated above picking up people who could have had the disease weeks if not months ago. They are no longer infectious so are no longer a threat.
We are asking them and their contacts to isolate unnecessarily.
Reduce the number of cycles used in the labs so that you are targeting those that are a risk thus reduce the strain on test and trace and the number of people being asked to isolate.
...and in the process end up with an increase in false negatives.
Can't think why they haven't done this... "
Can you provide evidence for that. ? |
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Let's get one thing straight here, the PCR is all we have for masse test at the moment so like or not, That's it.
Lateral flow test will compliment the PCR test and also looks for viral fragments.
Both will show if a person has the virus or has had the virus previously.
So in theory, it could show that someone who is no longer infectious is positive..
That's unfortunate but the reality of the situation.
What that theory doesn't take into account is viral load.
It is now understood that those who are asymptomatic generally do not have a large viral load where as those who are unwell have a far greater viral load..
That made sense to me and seemed almost blatantly obvious, but I'm sure there is more at play than just quantity of virus in a system.
What this does mean is those with a lower viral load will be rid of any residual viral remains far quicker than someone who was unwell.
More obviously, the person who is unwell will (or should) go and get a test early on.
The person who is asymptomatic, if picked up as being positive, is more than likely to either still be infectious or very recently been infectious.
By informing the contacts of the asymptomatic person, it may be early enough in the procession of infection to limit or halt further infection to others.
Those isolating people are more likely to think about their health and consider getting tested if they feel even a little unwell.
It is a broad brush approach, sledgehammer to crack a nut and some people along the way will have to isolate unnecessarily.
But its all about breaking the chain and this is the only tool we have to do it.
As numbers come down, the ability for track and trace to be more effective increase, the ability to turn around testing quickly also increases. At that point, the whole system become much more efficient and periods of isolation can be reduced.
An analogy is a wildfire, when it's out of control It's impossible to contain no matter how much resource you throw at it. As soon as reduced, it becomes manageable, flareups can be contained thus preventing it from getting out of control again. |
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By (user no longer on site)
over a year ago
|
"Let's get one thing straight here, the PCR is all we have for masse test at the moment so like or not, That's it.
Lateral flow test will compliment the PCR test and also looks for viral fragments.
Both will show if a person has the virus or has had the virus previously.
So in theory, it could show that someone who is no longer infectious is positive..
That's unfortunate but the reality of the situation.
What that theory doesn't take into account is viral load.
It is now understood that those who are asymptomatic generally do not have a large viral load where as those who are unwell have a far greater viral load..
That made sense to me and seemed almost blatantly obvious, but I'm sure there is more at play than just quantity of virus in a system.
What this does mean is those with a lower viral load will be rid of any residual viral remains far quicker than someone who was unwell.
More obviously, the person who is unwell will (or should) go and get a test early on.
The person who is asymptomatic, if picked up as being positive, is more than likely to either still be infectious or very recently been infectious.
By informing the contacts of the asymptomatic person, it may be early enough in the procession of infection to limit or halt further infection to others.
Those isolating people are more likely to think about their health and consider getting tested if they feel even a little unwell.
It is a broad brush approach, sledgehammer to crack a nut and some people along the way will have to isolate unnecessarily.
But its all about breaking the chain and this is the only tool we have to do it.
As numbers come down, the ability for track and trace to be more effective increase, the ability to turn around testing quickly also increases. At that point, the whole system become much more efficient and periods of isolation can be reduced.
An analogy is a wildfire, when it's out of control It's impossible to contain no matter how much resource you throw at it. As soon as reduced, it becomes manageable, flareups can be contained thus preventing it from getting out of control again. "
Did you listen to the same podcast as me? |
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"
For gods sake Oxfords Centre for evidence based medicine have been raising this for months.
The current number of cycles used in the tests is as stated above picking up people who could have had the disease weeks if not months ago. They are no longer infectious so are no longer a threat.
We are asking them and their contacts to isolate unnecessarily.
Reduce the number of cycles used in the labs so that you are targeting those that are a risk thus reduce the strain on test and trace and the number of people being asked to isolate.
...and in the process end up with an increase in false negatives.
Can't think why they haven't done this...
Can you provide evidence for that. ?"
Why?
The scientific community can't agree how many cycles to use so anything I cite as evidence will be discredited by a different piece of evidence.
The test is what it is.
|
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"Let's get one thing straight here, the PCR is all we have for masse test at the moment so like or not, That's it.
Lateral flow test will compliment the PCR test and also looks for viral fragments.
Both will show if a person has the virus or has had the virus previously.
So in theory, it could show that someone who is no longer infectious is positive..
That's unfortunate but the reality of the situation.
What that theory doesn't take into account is viral load.
It is now understood that those who are asymptomatic generally do not have a large viral load where as those who are unwell have a far greater viral load..
That made sense to me and seemed almost blatantly obvious, but I'm sure there is more at play than just quantity of virus in a system.
What this does mean is those with a lower viral load will be rid of any residual viral remains far quicker than someone who was unwell.
More obviously, the person who is unwell will (or should) go and get a test early on.
The person who is asymptomatic, if picked up as being positive, is more than likely to either still be infectious or very recently been infectious.
By informing the contacts of the asymptomatic person, it may be early enough in the procession of infection to limit or halt further infection to others.
Those isolating people are more likely to think about their health and consider getting tested if they feel even a little unwell.
It is a broad brush approach, sledgehammer to crack a nut and some people along the way will have to isolate unnecessarily.
But its all about breaking the chain and this is the only tool we have to do it.
As numbers come down, the ability for track and trace to be more effective increase, the ability to turn around testing quickly also increases. At that point, the whole system become much more efficient and periods of isolation can be reduced.
An analogy is a wildfire, when it's out of control It's impossible to contain no matter how much resource you throw at it. As soon as reduced, it becomes manageable, flareups can be contained thus preventing it from getting out of control again. "
Well said sir  Can you get a job in government please |
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By (user no longer on site)
over a year ago
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"Are going to empty their postboxes 7 days a week in order to process covid-19 home test kits more quickly
This will only help speed the processing of tests posted on a weekend"
It will only be one collection on a Sunday as well |
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"Good on them , it all helps
Exactly how does the PCR test help?
The PCR test cannot distinguish the infectious live virus from residual dead virus or viral fragments from previous infection. Therefore, many, if not most, “cases” have no real meaning in terms of medical status or transmission potential – further misleading clinicians and policymakers alike.
Problems and inconsistencies with PCR testing have been documented extensively non standardised specimen collection techniques; no gold standard test yet identified; different tests used in different labs; no standardised acceptable Ct values; inconsistent quality assurance
programs; false positives; identification of irrelevant dead viral genetic material which can persist for months after infection; potential contamination of specimens, to name a few.
We have an epidemic of false test results not an epidemic of disease.
People need to realise that the test regime is scientifically nonsensical."
Is this your conclusion based on extensive knowledge and copious years study in relevant biological sciences or cuz you saws it on a video on utube? False positives are pretty low. If we had an epidemic of false positives then positive rates would track very closely with the number of tests conducted they don’t. If we had an epidemic of positive tests there would no regional differences in positive tests and hospitalisations rates yet there is. |
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By *ancsduoCouple
over a year ago
Morecambe |
"Are going to empty their postboxes 7 days a week in order to process covid-19 home test kits more quickly
This will only help speed the processing of tests posted on a weekend
It will only be one collection on a Sunday as well"
Most post boxes are only emptied once a day... |
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By (user no longer on site)
over a year ago
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"Are going to empty their postboxes 7 days a week in order to process covid-19 home test kits more quickly
This will only help speed the processing of tests posted on a weekend
It will only be one collection on a Sunday as well
Most post boxes are only emptied once a day..."
Some maybe, but some twice |
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In my area of Liverpool, there are signs on the post box asking people not to post their home tests in the post box, but to give it to the guy sitting next to the box in the fire and rescue vehicle. There must be so many getting processed, Royal Mail can't cope! Lol |
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By (user no longer on site)
over a year ago
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"In my area of Liverpool, there are signs on the post box asking people not to post their home tests in the post box, but to give it to the guy sitting next to the box in the fire and rescue vehicle. There must be so many getting processed, Royal Mail can't cope! Lol "
I process 1000s every night, tests coming in, and going out |
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"In my area of Liverpool, there are signs on the post box asking people not to post their home tests in the post box, but to give it to the guy sitting next to the box in the fire and rescue vehicle. There must be so many getting processed, Royal Mail can't cope! Lol
I process 1000s every night, tests coming in, and going out"
Mad! It's great that people are getting tested but it does feel like the mass testing in Liverpool was thrown out there without thinking about the current infrastructure and staff to deal with the added work! |
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By (user no longer on site)
over a year ago
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"Are going to empty their postboxes 7 days a week in order to process covid-19 home test kits more quickly
This will only help speed the processing of tests posted on a weekend
It will only be one collection on a Sunday as well
Most post boxes are only emptied once a day...
Some maybe, but some twice"
i only got one present for my anniversary, my friend got 2 for hers, my husband could have given me 2 but he was skint and spent the last of his resources on the one i got
whats my point? how is it relevant? its not
much like the fact some post boxes are emptied more than once on weekdays  |
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By (user no longer on site)
over a year ago
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"Are going to empty their postboxes 7 days a week in order to process covid-19 home test kits more quickly
This will only help speed the processing of tests posted on a weekend
It will only be one collection on a Sunday as well
Most post boxes are only emptied once a day...
Some maybe, but some twice
i only got one present for my anniversary, my friend got 2 for hers, my husband could have given me 2 but he was skint and spent the last of his resources on the one i got
whats my point? how is it relevant? its not
much like the fact some post boxes are emptied more than once on weekdays "
Point taken  p. S. I'm having broccoli for my tea |
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