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Possibly ..,
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By (user no longer on site)
over a year ago
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"No vaccine will ever be discovered they was saying last night , god do we have to live ours lives like this indefinitely, it’s depressing  "
No its just like nova virus and HIV we get on with it. |
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And the Dam WHO have the cheek to say be careful coming out of lockdown - it was the WHO who said there was no need to restrict travel in LATE JAN 2020 \
Might have been a good idea to close borders at the start of the discovery
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There's certainty over little in medicine and pharmaceuticals. I assume few of us, if any, are currently working on a prospective vaccine, so won't have much ability to gauge outcomes.
There are certainly many teams around the world employed for vaccine development for this virus, most of them with international collaboration, possibly at a level not seen before. The international demand is certainly extremely high, helping to increase the potential likelihood of getting one.
I'm taking the approach to minimise risk now, with the assumption that at least 1 vaccine will be available in the next couple of years to help to reduce it further.
That several teams are already in clinical trials with patients fills me with greater hope, as so many more of the teams may also be ready very quickly, compared to typical lead times, to get a result that can work. Obviously safety and effectiveness have to be demonstrated. The virus has mutated but very little, compared to many viruses, which gives me further call to be optimistic. |
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By (user no longer on site)
over a year ago
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It's a balancing act..
If there is no vaccine then the hope is establishing herd immunity..if that's possible/long lasting..
To get that..you need people to actually get it and recover..
So longer term no matter what..it's a case of being prepared to take sensible steps to prevent catching it...
My job has taken me into work..shared office at times...so..supplied with sterilisation spray,wipes, access to gloves masks as needed..keeping distance from others...so what we talking 6plus weeks of working and none of have come down with it..
The future though..is the longer term changes to a vast range of work...the impact of social distancing on life..like concerts, gigs, fund raising..the list is endless really... |
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By (user no longer on site)
over a year ago
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"No vaccine will ever be discovered they was saying last night , god do we have to live ours lives like this indefinitely, it’s depressing "
Not necessarily.
Go back to 'normal', let it spread naturally and brace for a couple of million deaths and the wrecking of the NHS |
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By (user no longer on site)
over a year ago
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"No vaccine will ever be discovered they was saying last night , god do we have to live ours lives like this indefinitely, it’s depressing
Not necessarily.
Go back to 'normal', let it spread naturally and brace for a couple of million deaths and the wrecking of the NHS "
That's exactly what will happen. Worldwide. Millions dead so plenty of jobs and houses for the survivors. Good times.  |
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"No vaccine will ever be discovered they was saying last night , god do we have to live ours lives like this indefinitely, it’s depressing
Not necessarily.
Go back to 'normal', let it spread naturally and brace for a couple of million deaths and the wrecking of the NHS
That's exactly what will happen. Worldwide. Millions dead so plenty of jobs and houses for the survivors. Good times. "
Offt  |
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By *lansmanMan
over a year ago
Sheffield |
"Seen a report online saying that theres 30+ mutations of the covid 19 so its impossible to make a vaccine for it dont know how true it is "
Viruses mutate all the time . I read that the sars virus mutated and became weaker towards the end of the 2003 epidemic . Hopefully a similar change might occur in this current covid19 pandemic . In fact in my opinion it might be our only hope . We cannot be locked down for years to come. |
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"And the Dam WHO have the cheek to say be careful coming out of lockdown - it was the WHO who said there was no need to restrict travel in LATE JAN 2020 \
Might have been a good idea to close borders at the start of the discovery
"
What the WHO says doesn't seem to matter very much to some countries (our own amongst them) |
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"Seen a report online saying that theres 30+ mutations of the covid 19 so its impossible to make a vaccine for it dont know how true it is "
I don't think this is correct. All viruses mutate, some more than others. Influenza virus mutates a lot, but there is still a vaccine, although it can't protect you from contracting influenza from a new strain. The good news is that coronaviruses don't mutate very much, although it's obviously early days with this particular one. There's grounds for cautious optimism, particularly given the effort being poured into developing a vaccine, although nothing is guaranteed. |
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By (user no longer on site)
over a year ago
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"Seen a report online saying that theres 30+ mutations of the covid 19 so its impossible to make a vaccine for it dont know how true it is
I don't think this is correct. All viruses mutate, some more than others. Influenza virus mutates a lot, but there is still a vaccine, although it can't protect you from contracting influenza from a new strain. The good news is that coronaviruses don't mutate very much, although it's obviously early days with this particular one. There's grounds for cautious optimism, particularly given the effort being poured into developing a vaccine, although nothing is guaranteed."
RNA (as opposed to DNA) is unstable so slight changes occur. It does not equate to the mutations on the level we see re the flu. That's not to say it won't.
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By (user no longer on site)
over a year ago
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"No vaccine will ever be discovered they was saying last night , god do we have to live ours lives like this indefinitely, it’s depressing "
We’re doomed we’re doomed |
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By *mmabluTV/TS
over a year ago
upton wirral |
"No vaccine will ever be discovered they was saying last night , god do we have to live ours lives like this indefinitely, it’s depressing "
I doubt if life will ever be quite the same but we will have a new normal,we will adapt it is how humanity has survived. |
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"No vaccine will ever be discovered they was saying last night , god do we have to live ours lives like this indefinitely, it’s depressing "
Even if there is no vaccine (ever) it does not mean life stays like this.
There is no vaccination for many viruses, the reason for the lock down was its high chronic rate of illness. But part of that is due to it being new to the species.
Even with no treatment or vaccination over the long term (3-4) years that chronic rate of illness would decline naturally.
But no political figure (even in a one party state like China) could possibly sell survival of the fittest...
So lock down mitigates and spreads out the impact over a longer and more socially acceptable period, it also allows immunity to build in the population providing some lowering of the risk for vulnerable groups.
But basically without a vaccine those in the vulnerable group are as likely to have bad outcomes today as they were on day one if they catch it.
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"Seen a report online saying that theres 30+ mutations of the covid 19 so its impossible to make a vaccine for it dont know how true it is
I don't think this is correct. All viruses mutate, some more than others. Influenza virus mutates a lot, but there is still a vaccine, although it can't protect you from contracting influenza from a new strain. The good news is that coronaviruses don't mutate very much, although it's obviously early days with this particular one. There's grounds for cautious optimism, particularly given the effort being poured into developing a vaccine, although nothing is guaranteed."
_
I believe what they mean is different strains. There's so many identified coronaviruses, thing about the coronavirus it tends to strictly remain to its species, I wouldn't be surprised if every mammal species on this planet has a strain of coronavirus affecting them since they don't effect us scientists aren't exactly at the forefront of trying to find out how many there are. In the last 2 decades there have been 3 zoonotic mutations which mutated into human form of the virus.
It's crossed the species barrier, all the coronaviruses are similar except when it comes to host and what effect it has on the host. Pigs have 4 identified strains of coronavirus each differing in the effects.
This strain of coronavirus we are tackling has an extraordinary effect. Most people catching it will be fine just like the other human versions. BUT this virus has an effect that's so severe on a particular genetic problem.
Anyone with a body that attacks itself is at risk. From types of arthritic conditions all the way to sepsis. For some reason this virus is triggering self destruction. A successful virus doesn't intend to kill the host it wants to replicate and live and infect as many organisms as possible.
This is why people who've worked with others who've been diagnosed without a doubt as having covid19 but remain only mild to moderate symptoms then another their symptoms range severe to critical yet they are a completely healthy individual otherwise. It's all down to predisposition.
Sepsis alone has over 30million documented cases per year globally, if those cases were each individuals rather than multiple diagnosis for some individuals.
Imagine the scale on which deaths will arise from these people catching the virus. This singular viral strain could be the most common cause of sepsis in the future.
In order to prevent these deaths need to crack the reason why the body overreacts to an infection or toxin. Then this virus will be no worse than common cold or mild flu when we can manage and reduce damage caused by sepsis and similar immune reactions such as Kawasaki disease.
The next question is which coronavirus will become zoonotic next and what does that have mean for the human race. Does this mean changing eating habits across the globe as all our farm animal produce has the potential to infect us.
Coronaviruses found in chickens, turkeys, pigs, cows will that make you think differently knowing only one person needs the virus that has been completely harmless to us to mutate then cause a pandemic.
We're juggling eggs ones bound to break and they just might all end up breaking as a result if we don't find a way to remain composed and balanced.
-- |
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By (user no longer on site)
over a year ago
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"Seen a report online saying that theres 30+ mutations of the covid 19 so its impossible to make a vaccine for it dont know how true it is
I don't think this is correct. All viruses mutate, some more than others. Influenza virus mutates a lot, but there is still a vaccine, although it can't protect you from contracting influenza from a new strain. The good news is that coronaviruses don't mutate very much, although it's obviously early days with this particular one. There's grounds for cautious optimism, particularly given the effort being poured into developing a vaccine, although nothing is guaranteed.
_
I believe what they mean is different strains. There's so many identified coronaviruses, thing about the coronavirus it tends to strictly remain to its species, I wouldn't be surprised if every mammal species on this planet has a strain of coronavirus affecting them since they don't effect us scientists aren't exactly at the forefront of trying to find out how many there are. In the last 2 decades there have been 3 zoonotic mutations which mutated into human form of the virus.
It's crossed the species barrier, all the coronaviruses are similar except when it comes to host and what effect it has on the host. Pigs have 4 identified strains of coronavirus each differing in the effects.
This strain of coronavirus we are tackling has an extraordinary effect. Most people catching it will be fine just like the other human versions. BUT this virus has an effect that's so severe on a particular genetic problem.
Anyone with a body that attacks itself is at risk. From types of arthritic conditions all the way to sepsis. For some reason this virus is triggering self destruction. A successful virus doesn't intend to kill the host it wants to replicate and live and infect as many organisms as possible.
This is why people who've worked with others who've been diagnosed without a doubt as having covid19 but remain only mild to moderate symptoms then another their symptoms range severe to critical yet they are a completely healthy individual otherwise. It's all down to predisposition.
Sepsis alone has over 30million documented cases per year globally, if those cases were each individuals rather than multiple diagnosis for some individuals.
Imagine the scale on which deaths will arise from these people catching the virus. This singular viral strain could be the most common cause of sepsis in the future.
In order to prevent these deaths need to crack the reason why the body overreacts to an infection or toxin. Then this virus will be no worse than common cold or mild flu when we can manage and reduce damage caused by sepsis and similar immune reactions such as Kawasaki disease.
The next question is which coronavirus will become zoonotic next and what does that have mean for the human race. Does this mean changing eating habits across the globe as all our farm animal produce has the potential to infect us.
Coronaviruses found in chickens, turkeys, pigs, cows will that make you think differently knowing only one person needs the virus that has been completely harmless to us to mutate then cause a pandemic.
We're juggling eggs ones bound to break and they just might all end up breaking as a result if we don't find a way to remain composed and balanced.
--"
Interesting read.
Thanks for that. |
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By *estivalMan
over a year ago
borehamwood |
"No vaccine will ever be discovered they was saying last night , god do we have to live ours lives like this indefinitely, it’s depressing "
we wont be living like this indefinatley.either a vaccine is found or. we learn to live with it and as time passes more and more people will pay it less and less attention. |
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Eventually we will give it no more thought like we do other things x 
