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Miracle pill produces same result as a gym workout
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The drug could revolutionise the lives of couch potatoes as it fills the body with a protein that is produced in the blood during strenuous workouts and it also slashes the appetite.
Scientists are now hoping to turn the drug into a medication that enables people to sweat it out without ever having to go to the gym and are also assessing the links between exercise and hunger.
Professor Yong Xu, from Baylor College of Medicine in the US, said: "Regular exercise has been proven to help weight loss, regulate appetite and improve the metabolic profile, especially for people who are overweight and obese.
"If we can understand the mechanism by which exercise triggers these benefits, then we are closer to helping many people improve their health."
Interesting concept..... |
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By (user no longer on site)
over a year ago
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That is such a fucking reach 
We understand the concept of working to make money, but if we understand the triggers of making money then we can do that not work at all  |
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By *hezGeekCouple
over a year ago
Bristol |
"How would that burn fat or build muscle?  surely if it just makes them sweat that'd just be water loss... "
My totally uninformed and unqualified guess would be that it works along the lines of fat metabolisers like Thermobol or Grenade,raising tbe resting heart rate slightly (or significantly with exercise) to burn more calories through accelerating the body's normal functions, as well as raising core temperature a bit to induce sweating and metabolisation.
.
No evidence or actual scientific knowledge to back this up though! |
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The saying is “there’s no such thing as a biological free lunch”
Strong effects come with strong side effects
We already have very strong fat burning drugs. DNP for example. You’ll just feel like death the entire time your on it and if you take too much you’ll literally cook yourself to death
The best pills we can hope for are strong appetite suppressants. We already have some in the form of ephedrine and clenbuterol. However the appetite suppressing effect becomes less strong with use.
I’m skeptical |
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Orrrrrrrrrr, people could read the actual research and realise that at no point did the researchers suggest a pill that would replace going to the gym for everyone. They've suggested that somehow increasing the levels of specific amino acids in the blood that are formed during intense exercise (byproducts of lactate), could be used to prevent things like osteoporosis etc. in elderly and disabled people who can no longer do weight bearing exercise. They also postulate that we could improve treatment of various metabolic diseases, such as diabetes, via the administration of these amino acids.
The reference is:
Li, V.L., He, Y., Contrepois, K. et al. An exercise-inducible metabolite that suppresses feeding and obesity. Nature (2022).
A good summary for the layperson can be read here:
Science Daily (online)
"The benefits of exercise in a pill? Science is closer to that goal" |
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"Orrrrrrrrrr, people could read the actual research and realise that at no point did the researchers suggest a pill that would replace going to the gym for everyone. They've suggested that somehow increasing the levels of specific amino acids in the blood that are formed during intense exercise (byproducts of lactate), could be used to prevent things like osteoporosis etc. in elderly and disabled people who can no longer do weight bearing exercise. They also postulate that we could improve treatment of various metabolic diseases, such as diabetes, via the administration of these amino acids.
The reference is:
Li, V.L., He, Y., Contrepois, K. et al. An exercise-inducible metabolite that suppresses feeding and obesity. Nature (2022).
A good summary for the layperson can be read here:
Science Daily (online)
"The benefits of exercise in a pill? Science is closer to that goal""
Why the fuck would we read the study when we can squabble over a headline.
The fuck outta here with your fancy reading |
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By (user no longer on site)
over a year ago
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"Orrrrrrrrrr, people could read the actual research and realise that at no point did the researchers suggest a pill that would replace going to the gym for everyone. They've suggested that somehow increasing the levels of specific amino acids in the blood that are formed during intense exercise (byproducts of lactate), could be used to prevent things like osteoporosis etc. in elderly and disabled people who can no longer do weight bearing exercise. They also postulate that we could improve treatment of various metabolic diseases, such as diabetes, via the administration of these amino acids.
The reference is:
Li, V.L., He, Y., Contrepois, K. et al. An exercise-inducible metabolite that suppresses feeding and obesity. Nature (2022).
A good summary for the layperson can be read here:
Science Daily (online)
"The benefits of exercise in a pill? Science is closer to that goal""
I'm too tired to read from all the exercise I did today  |
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"Orrrrrrrrrr, people could read the actual research and realise that at no point did the researchers suggest a pill that would replace going to the gym for everyone. They've suggested that somehow increasing the levels of specific amino acids in the blood that are formed during intense exercise (byproducts of lactate), could be used to prevent things like osteoporosis etc. in elderly and disabled people who can no longer do weight bearing exercise. They also postulate that we could improve treatment of various metabolic diseases, such as diabetes, via the administration of these amino acids.
The reference is:
Li, V.L., He, Y., Contrepois, K. et al. An exercise-inducible metabolite that suppresses feeding and obesity. Nature (2022).
A good summary for the layperson can be read here:
Science Daily (online)
"The benefits of exercise in a pill? Science is closer to that goal"
Why the fuck would we read the study when we can squabble over a headline.
The fuck outta here with your fancy reading "
Soz  |
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By (user no longer on site)
over a year ago
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Sounds like speed called something else to me and therefore very bad for you long term, also just a mere side note here….. we are the pinnacle of evolution, ability to change our environment all that, why can’t we tell the fat fucks to get off their arse…..is that too hard because last time I looked if there had been lazy cavemen, then no homo-erectus, just saying |
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By (user no longer on site)
over a year ago
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Well good times make people lazy and soft so we had it coming, has anyone ever tried dieting? It’s hard, exercise? That’s hard too, getting fat? No ithats Fucking easy, you just sit there and eat more calories than you burn job done, if someone is overweight because of a disability/ condition then they have my love and support in their life journey because I have empathy and a willingness to see people happy but there’s been people with no legs climb mountains so anyone denying themselves lettuce in favour of chocolate needs to look at why how and what to do not sit there and cry about it |
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"It will never get MHRA approval as a ‘lifestyle’ drug … "
It's not being suggested as a lifestyle drug. The medicinal application actually suggested is to reduce incidence of osteoporosis etc in people who are unable to be physically active, e.g. elderly and disabled people. |
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"Well good times make people lazy and soft so we had it coming, has anyone ever tried dieting? It’s hard, exercise? That’s hard too, getting fat? No ithats Fucking easy, you just sit there and eat more calories than you burn job done, if someone is overweight because of a disability/ condition then they have my love and support in their life journey because I have empathy and a willingness to see people happy but there’s been people with no legs climb mountains so anyone denying themselves lettuce in favour of chocolate needs to look at why how and what to do not sit there and cry about it "
Have you tried climbing a mountain without legs? Please do not venture to know exactly what exercise disabled people may or may not be able to do. It's not that straightforward and every disabled person is different.
My amputee friend cannot use a prostheses because of stump related problems. However, there's a general assumption that all amputees can just shove on a bionic limb and carry on regardless.
I know a wheelchair user who has taken his chair scuba diving. I also know who funded that adventure. What you will discover is that exercising with most physical disabilities is jolly expensive. The wheelchair I use for basketball (borrowed off a club) would have cost over £3,000. What does basketball cost to play as an able bodied person? My new regular day chair is costing me £4,400. I'm getting "free" off-road wheels but in my current chair (in the avatar image), it's just pure fucking struggle to go anywhere other than tarmac/concrete. My mate with an upper limb impairment struggles even to push on the pavement - he hasn't got a chance on slight inclines or uneven surfaces.
Exercising with disability is really, really hard and to suggest that because one dude with no legs once climbed a mountain, ergo everything is possible, is actually really unhelpful.
Yours in perpetuity,
A Disabled Person
(Who is very physically active. And a fat fucker  ) |
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By (user no longer on site)
over a year ago
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At no point have I suggested exercise is easy for anyone, I used to be very over weight myself and I did something about it, more than one amputee has climbed a mountain with no prosthetics not just one ‘dude’ and even though you aren’t asking I am more than aware of the difficulties faced by disabled people and exercise as I design carbon fibre parts for people with disabilities, speak to them on a daily basis, all of them are working on being better physically so hats off to you for doing the same, the fat fucks I was referring to are those that could do something about it but don’t and then get upset when called out for it but never mind woke culture and all that |
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"At no point have I suggested exercise is easy for anyone, I used to be very over weight myself and I did something about it, more than one amputee has climbed a mountain with no prosthetics not just one ‘dude’ and even though you aren’t asking I am more than aware of the difficulties faced by disabled people and exercise as I design carbon fibre parts for people with disabilities, speak to them on a daily basis, all of them are working on being better physically so hats off to you for doing the same, the fat fucks I was referring to are those that could do something about it but don’t and then get upset when called out for it but never mind woke culture and all that "
Please address the issue of the excessive cost of exercising as a disabled person? I have to fund all my own mobility equipment. The NHS provides basic prosthetic limbs but if you want a running blade or something specialist, you have to find charity funding or sell a kidney or something.
Basketball cost for able bodied child? Cheap trainers and a ball. Wheelchair basketball cost? Minimum £1500 for a non-bespoke size, heavy chair. There's your problem. |
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By *ucka39Man
over a year ago
Newcastle |
No pill is going to provide anything just the same as you can't get the benefits of any source of protein without using some kind of physical exercise no protein is classified as a meal it's a supplement it's not the matrix |
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"Orrrrrrrrrr, people could read the actual research and realise that at no point did the researchers suggest a pill that would replace going to the gym for everyone. They've suggested that somehow increasing the levels of specific amino acids in the blood that are formed during intense exercise (byproducts of lactate), could be used to prevent things like osteoporosis etc. in elderly and disabled people who can no longer do weight bearing exercise. They also postulate that we could improve treatment of various metabolic diseases, such as diabetes, via the administration of these amino acids.
The reference is:
Li, V.L., He, Y., Contrepois, K. et al. An exercise-inducible metabolite that suppresses feeding and obesity. Nature (2022).
A good summary for the layperson can be read here:
Science Daily (online)
"The benefits of exercise in a pill? Science is closer to that goal"
Why the fuck would we read the study when we can squabble over a headline.
The fuck outta here with your fancy reading "
I love thus 
The world would get on a lot better if people didn’t do that fancy reading stuff and actually really understand science and shit.
I say we go back to superstition and burning people because we don’t really understand stuff. Brilliant!  |
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